ntravitreal anti-VEGF injections are, colloquially speaking, drug injections with an ultra-thin needle into the eye. The name of the treatment comes from the vitreous – the substance that fills our eyes.
What is the procedure?
Injections (administration of the active substance) into the inside of the eyeball, and more precisely into the vitreous chamber. The procedure is uncomplicated, short and painless. Intravitreal administration of the drug is performed using aseptic techniques, using a very thin needle, in the treatment of diseases such as:
AMD – age-related retinal degeneration – exudative form,
macular edema associated with retinal vascular thrombosis.
The procedure is performed under local anesthesia. We perform injections with the following drugs: Lucentis , Eylea , Avastin , Ozurdex.
Lucentis specifically recognizes and binds to a protein called human vascular endothelial growth factor A (VEGF-A) in the eye. By binding to VEGF, Lucentis can block these effects and prevent this abnormal growth and swelling. The active substance is ranibizumab.
EYLEA® is a drug that belongs to the so-called VEGF inhibitors. VEGF inhibitors are factors that inhibit the action of VEGF, which describes the way EYLEA® works to protect eyesight. EYLEA® blocks a specific protein that causes leaking blood vessels to appear . The active substance in the preparation is aflibercept. As a result of the use of this drug, the swelling of the retina is reduced and vision is protected.
The active substance in AVASTIN is bevacizumab, which blocks vascular endothelial growth factor A (VEGF-A). Due to the fact that there is no registration, it is used all over the world “off label”, ie outside the registration indications. The patient must consent to such a formula for administering the drug.
Ozurdex – is a derivative of dexamethazone. The drug, manufactured in the form of an implant, is licensed specifically for intra-eye administration. Looks like a piece of automatic pencil refill, white in color. It differs from triamcinolone in that it does not cause floaters when injected into the eye. Its effect lasts from 4 to 6 months.